RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
circTAOK1
RNA ID
RNA Type
circRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR;western blot;dual-luciferase reporter etc.
Target
NA
Pathway
NA
PubMed ID
Title
Exosomal circTAOK1 contributes to diabetic kidney disease progression through regulating SMAD3 expression by sponging miR-520h
Year
2022
Function
"GEC-circTAOK1-Exo could boost proliferation, fibrosis, and epithelial-mesenchymal transition (EMT) of glomerular mesangial cells (GMCs) through targeting the miR-520h/SMAD3 axis, providing new insights into the pathogenesis of diabetic nephropathy."